Emma Pristo

New compound shrinks brain tumors in mice, sparking hope for a glioblastoma pill

January 28, 2026 Scientists have identified a small molecule called compound A that shrinks glioblastoma brain tumors in mice by targeting advillin (AVIL), a protein found at abnormally high levels in this aggressive cancer. Because AVIL regulates the cell’s actin cytoskeleton and lacks obvious drug-binding sites, it was long considered an extremely difficult target, but […]
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The Khasraw Lab presenting at the DCI Retreat

December 5, 2025 We would like to congratulate Jodie Jepson for presenting her abstract on Spatial Imaging of tumors being accepted as a podium presentation at the Duke Cancer Institute retreat. Also would like to congratulate Elizabeth Owens and Yichen Huang for having their abstracts on the PUMP trial and methylation differences in short and […]
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Lab Updates — Friday, October 10, 2025

Friday, October 10, marked Chelsea Railtons last day with us as she embarks on an exciting new role at a CRO that offers fresh challenges and opportunities for growth. Over the past three years, Chelsea has become an essential part of nearly everything we do, from cell culture and single cell library prep to clinical […]
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Presentations at EANO 2025

On October 17–18, members of our lab presented three talks at the European Association of Neuro-Oncology (EANO) Annual Meeting in Prague, including two selected for plenary sessions. These presentations highlighted recent findings from the PuMP and ETAPA clinical trials, as well as ongoing work from our tumor-infiltrating lymphocyte (TIL) program. We are proud to see […]
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